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Upper Mississippi River Cruise

<p>Set off on an exhilarating journey on the Upper Mississippi River, where every moment resonates with the essence of hometown Americana and the breathtaking beauty that has captivated the imaginations of our nation's most revered writers, artists, and musicians. Feel the heartbeat of the great American spirit as you follow in the footsteps of literary legend Mark Twain, who found inspiration amidst the grandeur of the river and its cascading bluffs, immortalizing them in his iconic tales. Step into the pages of history as you travel to Hannibal, the very town that shaped Twain's storytelling, where the colorful characters of Huck Finn, Tom Sawyer, and Becky Thatcher spring to life.&nbsp;</p>
<p>From the comfort of your own private balcony, take in the unspoiled landscapes, adorned with playful wildlife. Navigate through a labyrinth of enchanting islands and get up close to the ingenious engineering of dams and locks.</p>
<p>As the river twists and turns, all your meals will reflect the landscape you pass. Every dish is thoughtfully curated, infused with the essence of local ingredients, ensuring each bite is a celebration of the rich culture that lines the shores of the upper Mississippi. Join us and let the energy of this remarkable journey ignite your spirit and leave you with memories to cherish for a lifetime.</p>
<p>Just as it was back in Mark Twain&rsquo;s day, every cruise on the Upper Mississippi River is unique due to fluctuating river conditions that can have an impact on our itinerary.&nbsp;</p>
04 July, 2025 to 12 July, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
11 July, 2025 to 19 July, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
18 July, 2025 to 26 July, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
25 July, 2025 to 02 August, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
01 August, 2025 to 09 August, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
08 August, 2025 to 16 August, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
15 August, 2025 to 23 August, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
22 August, 2025 to 30 August, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
29 August, 2025 to 06 September, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
05 September, 2025 to 13 September, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
12 September, 2025 to 20 September, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
19 September, 2025 to 27 September, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
26 September, 2025 to 04 October, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
03 October, 2025 to 11 October, 2025
Cabin. From $6,575 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
10 October, 2025 to 18 October, 2025
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
12 June, 2026 to 20 June, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
03 July, 2026 to 11 July, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
10 July, 2026 to 18 July, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
17 July, 2026 to 25 July, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
24 July, 2026 to 01 August, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
31 July, 2026 to 08 August, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
07 August, 2026 to 15 August, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
14 August, 2026 to 22 August, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
21 August, 2026 to 29 August, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
28 August, 2026 to 05 September, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
04 September, 2026 to 12 September, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
11 September, 2026 to 19 September, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
18 September, 2026 to 26 September, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
25 September, 2026 to 03 October, 2026
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
02 October, 2026 to 10 October, 2026
Cabin. From $5,995 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
09 October, 2026 to 17 October, 2026
Cabin. From $5,995 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
11 June, 2027 to 19 June, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
02 July, 2027 to 10 July, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
09 July, 2027 to 17 July, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
16 July, 2027 to 24 July, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
23 July, 2027 to 31 July, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
30 July, 2027 to 07 August, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
06 August, 2027 to 14 August, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
13 August, 2027 to 21 August, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
20 August, 2027 to 28 August, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
27 August, 2027 to 04 September, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
03 September, 2027 to 11 September, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
10 September, 2027 to 18 September, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
17 September, 2027 to 25 September, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
24 September, 2027 to 02 October, 2027
Cabin. From $5,635 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
01 October, 2027 to 09 October, 2027
Cabin. From $5,995 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo
08 October, 2027 to 16 October, 2027
Cabin. From $5,995 USD pp
Our staterooms are the most spacious in the small ship cruising industry. All range between 200 and 450 square feet in size, and feature full-size bathrooms and modern amenities. After an invigorating day, your spacious stateroom is a comfortable haven and the perfect place to relax and unwind. Enjoy the ever-changing scenery from your large opening picture window or from your private balcony.
view cabin photo

Upper Mississippi River Cruise itinerary:

show reverse itinerary
Day 1 - St. Louis, MO/Alton, IL

Tucked away beneath the limestone bluffs lies the charming port of Alton, Illinois, serving as a gateway to endless adventures in St. Louis and beyond. But before you set off on your escapades, start your journey with a visit to the captivating National Great Rivers Museum. Learn about the fascinating tales of the mighty upper Mississippi River, exploring its extensive history, the communities it sustains, and the diverse ecosystems it nurtures.

Day 2 - Cruising the Upper Mississippi River

With the wide Mississippi before you, relish the quiet sounds of the river. Relax on your private balcony and watch the riverbanks come to life with a vast array of wildlife that calls these shores home or learn the stories of the area around you from the on-board expert. Make sure to wander to the sun deck for the best views of the winding river. But don’t forget to stop by the restaurant for freshly baked cookies at 3 pm daily. 

Day 3 - Hannibal, MO

Welcome to Hannibal, Missouri, a charming riverside town brimming with character. At the heart of Hannibal lies the legacy of its most famous resident, Mark Twain, whose childhood adventures served as the inspiration for some of literature's most beloved characters. Explore Twain's boyhood home, a beautifully preserved white clapboard house where the author spent his formative years. Nearby, the Mark Twain Boyhood Home & Museum offers a fascinating glimpse into Twain's life and works, including original manuscripts, rare artifacts, and interactive exhibits that bring his stories to life in vivid detail.

But Hannibal is more than just a literary landmark. Take a leisurely stroll down Main Street, where charming boutiques, art galleries, and antique shops beckon with unique finds and friendly smiles. Don't miss the Rockcliffe Mansion, registered as a historic home, and has breathtaking views of the Mississippi River while you learn about the history of Hannibal. 

Day 4 - Day of Cruising

A day on the river is not a day lost. Grab a book, a friend, a game, or an onboard expert and take the day as it comes as we navigate the upper Mississippi from Hannibal to Muscatine, IA. Engage in curated activities, from destination-focused enrichment programs led by esteemed guest speakers to stimulating Art and App-titude Classes and group Cooking Demonstrations. Embrace spirited camaraderie with Mixology sessions, Trivia challenges, and Game Shows. 

Day 5 - Muscatine, IA

Muscatine has a unique claim to fame as the only place where the Mighty Mississippi River runs east to west. This charming town is renowned for its history as the former largest button manufacturing area in the world, a claim to fame celebrated through local museums and historic sites. Visitors are enchanted by Muscatine's picturesque riverfront, offering stunning views and recreational opportunities such as boating and fishing. 

Downtown Muscatine invites exploration with its eclectic mix of boutique shops, cozy cafes, and vibrant eateries, all within just two blocks of our dock.

Day 6 - Dubuque, IA

Dubuque is a true masterpiece along the upper Mississippi River. As one of the oldest settlements west of the great river, Dubuque wears its history proudly while staying a modern hub for commerce, industry, education, and culture.

Step off the ship and into the renowned National Mississippi River Museum & Aquarium, a mesmerizing complex that promises to captivate your senses. Wander through the charming streets adorned with picturesque Victorian mansions, feel the thrill of riding the world's shortest and steepest scenic railway, or visit one of its oldest Catholic churches, and then the Dubuque Arboretum & Botanical Garden. 

Day 7 - Winona, MN

Situated in southeastern Minnesota along the banks of the upper Mississippi River, Winona is a gem of a city renowned for its stunning bluffs, picturesque riverfront, and blend of cultures.

The city's architecture is a captivating mesh of styles, ranging from the grandeur of the Beaux-Arts-style Winona County Courthouse to the intricate details of the Victorian-era homes in the historic district. The Winona National Bank Building, with its striking neoclassical facade, and the Basilica of St. Stanislaus Kostka with Polish Cathedral-style architecture are breathtaking examples of what lies in this small Minnesotan town.

Winona's cultural scene is equally impressive, anchored by the Minnesota Marine Art Museum, which houses an impressive collection of marine art spanning centuries. 

Outdoor enthusiasts rejoice as there are plenty of scenic trails to explore at Garvin Heights Park. With complete panoramic views of the river valley below, and the tranquil waters of Lake Winona, this area is perfect for kayaking and paddleboarding.

Day 8 - Red Wing, MN

One of the most iconic features of Red Wing is Barn Bluff, a towering limestone bluff that overlooks the city and provides panoramic views of the surrounding landscape. Hiking trails wind their way to the summit, offering outdoor enthusiasts the opportunity to experience the area's natural beauty up close.

Red Wing is also famous for its pottery, thanks to the presence of the Red Wing Stoneware Company, which has been producing high-quality ceramics since the 19th century. Visitors can tour the pottery factory, browse the showroom, and even try their hand at creating their own pottery.

History buffs will delight in exploring the city's historic downtown district, where beautifully preserved buildings house charming boutiques, antique shops, and art galleries. The Red Wing Shoe Company Museum offers a fascinating glimpse into the history of the iconic footwear brand, while the Goodhue County Historical Society provides insight into the area's rich past.

Day 9 - St. Paul, MN

In St. Paul, a stroll down Summit Avenue unveils a captivating array of historic mansions, each with its own story to tell from the late 1800s. For a shopping extravaganza like no other, venture into the vast expanse of the Mall of America, boasting over 500 stores alongside an indoor water park and theme park. And don't miss the opportunity to visit the natural wonder of the 53-foot Minnehaha Falls, which cascade into a serene oasis, enveloping visitors in its enchanting charm.

We’ll disembark with convenient access to the Minneapolis/St. Paul airport. Or choose to indulge in an extended stay to fully experience this captivating region. 

Please note:

Itineraries are subject to change.

Upper Mississippi River Cruise reverse itinerary:

show main itinerary
Please note: *

Itineraries are subject to change.

Day 9 - St. Paul, MN *

In St. Paul, a stroll down Summit Avenue unveils a captivating array of historic mansions, each with its own story to tell from the late 1800s. For a shopping extravaganza like no other, venture into the vast expanse of the Mall of America, boasting over 500 stores alongside an indoor water park and theme park. And don't miss the opportunity to visit the natural wonder of the 53-foot Minnehaha Falls, which cascade into a serene oasis, enveloping visitors in its enchanting charm.

We’ll disembark with convenient access to the Minneapolis/St. Paul airport. Or choose to indulge in an extended stay to fully experience this captivating region. 

Day 8 - Red Wing, MN *

One of the most iconic features of Red Wing is Barn Bluff, a towering limestone bluff that overlooks the city and provides panoramic views of the surrounding landscape. Hiking trails wind their way to the summit, offering outdoor enthusiasts the opportunity to experience the area's natural beauty up close.

Red Wing is also famous for its pottery, thanks to the presence of the Red Wing Stoneware Company, which has been producing high-quality ceramics since the 19th century. Visitors can tour the pottery factory, browse the showroom, and even try their hand at creating their own pottery.

History buffs will delight in exploring the city's historic downtown district, where beautifully preserved buildings house charming boutiques, antique shops, and art galleries. The Red Wing Shoe Company Museum offers a fascinating glimpse into the history of the iconic footwear brand, while the Goodhue County Historical Society provides insight into the area's rich past.

Day 7 - Winona, MN *

Situated in southeastern Minnesota along the banks of the upper Mississippi River, Winona is a gem of a city renowned for its stunning bluffs, picturesque riverfront, and blend of cultures.

The city's architecture is a captivating mesh of styles, ranging from the grandeur of the Beaux-Arts-style Winona County Courthouse to the intricate details of the Victorian-era homes in the historic district. The Winona National Bank Building, with its striking neoclassical facade, and the Basilica of St. Stanislaus Kostka with Polish Cathedral-style architecture are breathtaking examples of what lies in this small Minnesotan town.

Winona's cultural scene is equally impressive, anchored by the Minnesota Marine Art Museum, which houses an impressive collection of marine art spanning centuries. 

Outdoor enthusiasts rejoice as there are plenty of scenic trails to explore at Garvin Heights Park. With complete panoramic views of the river valley below, and the tranquil waters of Lake Winona, this area is perfect for kayaking and paddleboarding.

Day 6 - Dubuque, IA *

Dubuque is a true masterpiece along the upper Mississippi River. As one of the oldest settlements west of the great river, Dubuque wears its history proudly while staying a modern hub for commerce, industry, education, and culture.

Step off the ship and into the renowned National Mississippi River Museum & Aquarium, a mesmerizing complex that promises to captivate your senses. Wander through the charming streets adorned with picturesque Victorian mansions, feel the thrill of riding the world's shortest and steepest scenic railway, or visit one of its oldest Catholic churches, and then the Dubuque Arboretum & Botanical Garden. 

Day 5 - Muscatine, IA *

Muscatine has a unique claim to fame as the only place where the Mighty Mississippi River runs east to west. This charming town is renowned for its history as the former largest button manufacturing area in the world, a claim to fame celebrated through local museums and historic sites. Visitors are enchanted by Muscatine's picturesque riverfront, offering stunning views and recreational opportunities such as boating and fishing. 

Downtown Muscatine invites exploration with its eclectic mix of boutique shops, cozy cafes, and vibrant eateries, all within just two blocks of our dock.

Day 4 - Day of Cruising *

A day on the river is not a day lost. Grab a book, a friend, a game, or an onboard expert and take the day as it comes as we navigate the upper Mississippi from Hannibal to Muscatine, IA. Engage in curated activities, from destination-focused enrichment programs led by esteemed guest speakers to stimulating Art and App-titude Classes and group Cooking Demonstrations. Embrace spirited camaraderie with Mixology sessions, Trivia challenges, and Game Shows. 

Day 3 - Hannibal, MO *

Welcome to Hannibal, Missouri, a charming riverside town brimming with character. At the heart of Hannibal lies the legacy of its most famous resident, Mark Twain, whose childhood adventures served as the inspiration for some of literature's most beloved characters. Explore Twain's boyhood home, a beautifully preserved white clapboard house where the author spent his formative years. Nearby, the Mark Twain Boyhood Home & Museum offers a fascinating glimpse into Twain's life and works, including original manuscripts, rare artifacts, and interactive exhibits that bring his stories to life in vivid detail.

But Hannibal is more than just a literary landmark. Take a leisurely stroll down Main Street, where charming boutiques, art galleries, and antique shops beckon with unique finds and friendly smiles. Don't miss the Rockcliffe Mansion, registered as a historic home, and has breathtaking views of the Mississippi River while you learn about the history of Hannibal. 

Day 2 - Cruising the Upper Mississippi River *

With the wide Mississippi before you, relish the quiet sounds of the river. Relax on your private balcony and watch the riverbanks come to life with a vast array of wildlife that calls these shores home or learn the stories of the area around you from the on-board expert. Make sure to wander to the sun deck for the best views of the winding river. But don’t forget to stop by the restaurant for freshly baked cookies at 3 pm daily. 

Day 1 - St. Louis, MO/Alton, IL *

Tucked away beneath the limestone bluffs lies the charming port of Alton, Illinois, serving as a gateway to endless adventures in St. Louis and beyond. But before you set off on your escapades, start your journey with a visit to the captivating National Great Rivers Museum. Learn about the fascinating tales of the mighty upper Mississippi River, exploring its extensive history, the communities it sustains, and the diverse ecosystems it nurtures.

* = Indicative
Map for Upper Mississippi River Cruise
American Cruise Line Ships, the ship servicing Upper Mississippi River Cruise

American Cruise Line Ships

Fleet of Small Ships
American Cruise Lines offers the newest fleet in America, each ship accommodating just 90 to 180 guests. We offer 6 unique ship styles, including a new class of Patriot Class, Coastal Cats, Classic Paddlewheelers, Constellation Class Ships, Independence Class, and the only modern American Riverboats. We have become the industry leader by continuing to introduce new and innovative ships each year, with the most diverse fleet in the country.

These new ships, built at Chesapeake Shipbuilding in Maryland, are a testament to premier nautical engineering and safety equipment, as well as state-of-the-art navigation. On board a sophisticated aesthetic, an unprecedented level of comfort, the largest staterooms globally, with full private balconies where indicated, and modern accommodations including high-speed internet powered by Starlink.

Our fleet allows us to provide a genuine and customized exploration of areas inaccessible to large ships and crowds, and to explore each region in the most meaningful way possible. With land never out of sight allowing for more time to savor the scenery. Our small ship river cruises offer a more intimate look at American cities from charming small towns to gracious southern ports.

American Riverboats | 180 Guests
American Serenade - American Symphony - American Melody - American Jazz - American Song - American Harmony

• Operates along the U.S. Rivers
• Multiple Dining Venues
• Sophisticated and Modern Décor 
• Outdoor Walking Track and Fitness Center
• Multi-Story Glass Atrium
• Unique Bow Ramp for Easy Boarding
• Elevator Access to All Passenger Decks

Coastal Cats Cruise Ships | 100 Guests
American Eagle - American Glory - American Liberty - American Legend

• Shallow Draft for Inland Exploration
• Modern Interior Design
• Multiple Dining Venues
• Bow Observation Area for Scenic Viewing
• Sun Deck with Walking Track
• Activity / Tender Platform
• Fitness Center
• Elevator Access to Each Deck

Constellation Class Coastal Ships | 170 Guests
American Constellation - American Constitution

• Traditional Bow for Coastal Travel
• Main Deck Restaurant with 270º Views
• Sun Deck with Shaded Lounge Area
• Entertainment Lounge
• Reading Lounge
• Fitness Center
• Elevator Access to All Passenger Decks

Paddlewheelers | 180 Guests
American Heritage - American Splendor - American Pride - American West

• Classic Paddlewheel Aesthetic
• Glass-Enclosed Restaurant 
• Open Seating Dining
• Three Distinct Guest Lounges 
• Cozy Study Enclave
• Fitness Center
• Elevator Access to All Passenger Decks

Independence Class Coastal Ships | 90 Guests
American Independence - American Spirit - American Star

• Traditional Bow for Coastal Travel
• Main Deck Restaurant with 270º Views
• Sun Deck with Shaded Lounge Area
• Entertainment Lounge
• Reading Lounge
• Fitness Center
• Elevator Access to All Passenger Decks

Patriot Class Coastal Ships | 125 Guests
American Patriot - American Pioneer

• Uniquely Designed Bow for Deeper Drafts
• Luxurious Grand Suites
• Open Seating Dining
• Multiple Guest Lounges
• Bow Terrace for Observation
• Fitness Center
• Elevator Access to All Decks

Cabin layout for American Cruise Line Ships
• Surround yourself with the river landscapes that inspired Mark Twain, from St. Louis to Hannibal to St. Paul.

• Explore the scenic bluffs, gardens, and homes that define the region.